Blood Relations

Lost Boys/Twilight

As the first of Max’s vampire children, David is in many ways alone. Then he meets someone who is almost—but not quite—like him.

Second Place

Jem and the Holograms (IDW Comics)

The fall and rise (and fall) (and rise) of the Limp Lizards.

Strange Lives

Teen Wolf

MURDER! ROMANCE! INTRIGUE! WEREWOLVES!

Derek is a werewolf. Stiles is a federal agent who investigates supernatural phenomena. And there are an assortment of werewolves, vigilante monster hunters, witches, and interdimensional shapeshifters who want them both dead.

Symbiosis

Project Hail Mary/Iron Lung/Farscape

Ryland Grace gets shot through a wormhole and ends up on a living ship full of strange alien lifeforms.

Or: the BloodyMary Farscape AU.